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Anti-S1P4, C-Terminal antibody produced in rabbit
| 产品编号： | 3393366 |
| 规格： | ~1 mg/mL, fractionated antiserum, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-S1P4, C-Terminal antibody produced in rabbit
Anti-EDG-6
Anti-Endothelial Cell Differentiation Gene 6
基本信息
| MDL number | MFCD03454969 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | synthetic peptide (approximately 2.5 kDa, native) derived from the C-terminal region of the EDG-6/S1P4 receptor. |
| Application【应用】 | Anti-S1P4, C-Terminal antibody produced in rabbit is suitable for western blotting at a working concentration of 5 to 10 μg/ml using COS cells transfected with full length EDG-6. |
| Biochem/physiol Actions【生化/生理作用】 | Sphingosine-1-phosphate receptor 4 (S1PR4, EDG-6) is a human gene which encodes a G protein-coupled receptor and is identified as an orphan G-protein-coupled receptor. It binds the lipid signaling molecule sphingosine 1-phosphate (S1P). EDG-6 is a member of the endothelial differentiation gene (EDG) G protein-coupled receptor family. It is expressed in lymphoid, hematopoietic tissue and in the lung. EDG-6 acts as a high affinity receptor for SPP that couples to a G(i/o) protein leading to the activation of growth-related signaling pathways. It is one of the S1P or lysosphingolipid receptors that couples to phospholipase C-Ca2+ system through pertussis toxin-sensitive G-proteins. |
| Physical form【外形】 | Supplied in phosphate buffered saline, pH 7.3, and 0.08% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | fractionated antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~45 kDa by SDS-PAGE |
| species reactivity | human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | O95977 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... S1PR4(8698) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
