您的位置：首页 > 产品中心 > Anti-S1P5, C-Terminal antibody produced in rabbit
Anti-S1P5, C-Terminal antibody produced in rabbit
| 产品编号： | 3393367 |
| 规格： | ~1 mg/mL, fractionated antiserum, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-S1P5, C-Terminal antibody produced in rabbit
Anti-Endothelial Cell Differentiation Gene 8
Anti-Edg-8
基本信息
| MDL number | MFCD03454973 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | synthetic peptide (approximately 2.5 kDa, native) derived from the C-terminal region of the EDG-8/S1P5 receptor. |
| Application【应用】 | Anti-S1P5, C-Terminal antibody produced in rabbit is suitable for western blotting at a working concentration of 5 to 10 μg/ml using RH7777 cells transfected with full length human EDG-8. |
| Biochem/physiol Actions【生化/生理作用】 | Sphingosine-1-phosphate receptor 5 (S1PR5) is a human gene which encodes a G protein-coupled receptor. It binds to lipid signaling molecule sphingosine 1-phosphate (S1P). S1PR5 regulates NK cell migration and distribution by interacting with sphingosine-1-phosphate (S1P). In brain endothelial cells (ECs), it contributes to optimal barrier formation and maintains immune quiescence of the barrier endothelium. S1PR5 is localized in the centrosome of mammalian cells and may participate in regulating mitosis. It may function as an intracellular target of S1P linked to regulation of mitosis. |
| Physical form【外形】 | Supplied in phosphate buffered saline, pH 7.3, containing 0.08% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | fractionated antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~42 kDa by SDS-PAGE |
| species reactivity | human |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q9H228 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... S1PR5(53637) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
