Anti-SIRT1 antibody produced in rabbit

NA.41

Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae) (SIRT1), a member of the NAD⁽⁺⁾-dependent protein deacetylase SIRT family, is involved in the regulation of nuclear transcription of genes involve in energy metabolism. SIRT1 provides a link between cellular energy status sensing (NAD⁽⁺⁾ status) and the regulation of energy homoeostasis. SIRT1 is involved in the regulation of metabolism, cell differentiation and senescence, stress response, and cancer.
Rabbit polyclonal anti-SIRT1 antibody reacts with chicken, human, mouse, rat, canine, and pig sirtuin-1 enzymes.

Synthetic peptide directed towards the N terminal region of human SIRT1

Rabbit polyclonal anti-SIRT1 antibody is used to tag sirtuin-1 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of sirtuin-1 in NAD⁽⁺⁾ status-dependent energy homeostasis at the level of nuclear transcription control and protein deacetylation.
Rabbit Anti-SIRT1 antibody can be used for western blot applications at a concentration of 0.5μg/ml.

SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined;

Synthetic peptide located within the following region: PETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKI

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

82 kDa

rat, dog, guinea pig, rabbit, horse, bovine, mouse, human

0.5 mg - 1 mg/mL

western blot: suitable

NP_036370

Q96EB6

wet ice

−20℃

human ... SIRT1(23411)

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12 - Non Combustible Liquids

WGK 3