Anti-SIRT5 antibody produced in chicken

NA.41

SIRT5 (Sirtuin 5) is a mitochondrial matrix protein belonging to the class III of the sirtuin family. It is localized inside the mitochondria and within the cytosol and nucleus. The protein is widely expressed in the brain, heart, liver and kidney. It is composed of very short amino and carboxyl terminal sequences flanking region with the conserved, catalytic sirtuin center domain.

SIRT5 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SIRT5.

Anti-SIRT5 antibody produced in chicken is suitable for western blot and indirect ELISA.

SIRT5 (Sirtuin 5) is associated with metabolism and aging process. It has been reported in a study that SIRT5 influences urea cycle pathway by NAD-dependent deacetylation and subsequent activation of carbamoyl phosphate synthetase 1 (CPS1), which plays a vital role in the initial step of urea cycle for the detoxification and removal of ammonia. In non-small cell-lung cancer cells. SIRT5 contributions have also been observed for the cancer cell growth and drug resistance. Study shows that SIRT5 may possess oncogenic property.

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The action of this antibody can be blocked using blocking peptide SBP3500496.

Supplied in PBS with 0.02% sodium azide.

chicken

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

human, mouse

indirect ELISA: suitable
western blot: suitable

NP_036373

Q9NXA8

dry ice

−20℃

human ... SIRT5(23408)

12 - Non Combustible Liquids