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Anti-SLC12A3 antibody produced in rabbit
产品别名
Anti-SLC12A3 antibody produced in rabbit
Anti-NCC
Anti-Slc12a3
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Solute carrier family 12 member 3 (SLC12A3) is also known as thiazide-sensitive Na+-Cl- cotransporter (NCCT). It is expressed in the apical cells of the distal convoluted tubule. The gene encoding this 1021 amino acid protein is localized on human chromosome 16q13. The gene ID for the protein is 6559. |
| Specificity【特异性】 | Detects ~160 kDa. |
| Immunogen【免疫原】 | AA74-95 (rat), 76-97 (hum) |
| Biochem/physiol Actions【生化/生理作用】 | Solute carrier family 12 member 3 (SLC12A3) is one of the major components of the sodium chloride reabsorption pathway. It controls the Cl- concentration and is also involved in the transepithelial ion absorption and secretion. Mutations in the gene encoding SLC12A3 have been associated with Gitelman syndrome. This Na-Cl cotransporter is associated with maintaining blood pressure. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | PBS, 50% glycerol, and 0.09% sodium azide |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous glycerol solution |
| mol wt【分子量】 | antigen predicted mol wt 160 kDa |
| species reactivity | mouse, rat, human |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_000330 NP_062218 |
| UniProt accession no.【UniProt登记号】 | P55017 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SLC12A3(6559) rat ... Slc12a3(54300) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
