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Anti-SND1 antibody produced in rabbit
产品别名
Anti-SND1 antibody produced in rabbit
Anti-Staphylococcal nuclease and tudor domain containing 1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | SND1 forms a part of the RNA-induced silencing complex (RISC) that regulates transcription. Studies have reported that SND1 is upregulated in colon cancer and is also involved in carcinogenesis. Rabbit Anti-SND1 antibody recognizes canine, zebrafish, chicken, human, mouse, rat, and bovine SND1. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N terminal region of human SND1 |
| Application【应用】 | Rabbit Anti-SND1 antibody can be western blot applications at a concentration of 1.25μg/ml. |
| Biochem/physiol Actions【生化/生理作用】 | SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN)-like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery |
| Sequence【序列】 | Synthetic peptide located within the following region: LPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQ |
| Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 100 kDa |
| species reactivity | dog, guinea pig, horse, rat, bovine, human, mouse, rabbit |
| concentration【浓度】 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_055205 |
| UniProt accession no.【UniProt登记号】 | Q7KZF4 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SND1(27044) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
