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Anti-SSH3 antibody produced in rabbit

产品编号:3398016
规格:purified immunoglobulin, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3398016100 μG4610
产品别名

Anti-SSH3 antibody produced in rabbit

SSH-3

FLJ10928

FLJ20515

基本信息
NACRES
NA.41
General description【一般描述】
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM
Immunogen【免疫原】
SSH3 (AAH07709.1, 1 a.a. ~ 659 a.a) full-length human protein.

Sequence
MALVTVSRSPPGSGASTPVGPWDQAVQRRSRLQRRQSFAVLRGAVLGLQDGGDNDDAAEASSEPTEKAPSEEELHGDQTDFGQGSQSPQKQEEQRQHLHLMVQLLRPQDDIRLAAQLEAPRPPRLRYLLVVSTREGEGLSQDETVLLGVDFPDSSSPSCTLGLVLPLWSDTQVYLDGDGGFSVTSGGQSRIFKPISIQTMWATLQVLHQACEAALGSGLVPGGSALTWASHYQERLNSEQSCLNEWTAMADLESLRPPSAEPGGSSEQEQMEQAIRAELWKVLDVSDLESVTSKEIRQALELRLGLPLQQYRDFIDNQMLLLVAQRDRASRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREIDNFYPERFTYHNVRLWDEESAQLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQELRPIARPNPGFLRQLQIYQGILTASRQSHVWEQKVGGVSPEEHPAPEVSTPFPPLPPEPEGGGEEKVVGMEESQAAPKEEPGPRPRINLRGVMRSISLLEPSLELESTSETSDMPEVFSSHESSHEEPLQPFPQLARTKGGQQVDRGPQPALKSRQSVVTLQGSAVVANRTQAFQEQEQGQGQGQGEPCISSTPRFRKVVRQASVHDSGEEGEA
Biochem/physiol Actions【生化/生理作用】
SSH3 (Slingshot protein phosphatase 3) is involved in the actin filament assembly. During actin reorganization, LIM-kinase 1 (LIMK1) restricts the activity of ADF (actin-depolymerizing factor)/cofilin, which is a stimulus-responsive mediator of actin dynamics. SSH3 blocks the LIMK1 functions and reactivates ADF/cofilin in vivo by the dephosphorylating it. In addition, it is also involved in several cellular and developmental activities.
Physical form【外形】
Solution in phosphate buffered saline, pH 7.4
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
antigen 73 kDa
species reactivity
human, mouse
technique(s)
western blot: 1 μg/mL
NCBI accession no.【NCBI登记号】
BC007709.1
UniProt accession no.【UniProt登记号】
Q8TE77
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... SSH3(54961)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 3
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