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Anti-STEAP2 antibody produced in rabbit
| 产品编号： | 3398385 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-STEAP2 antibody produced in rabbit
Anti-Six transmembrane epithelial antigen of the prostate 2
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The Six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a metalloreductase that belongs to the STEAP family. It is localized in secretory and endocytic pathway organelles. The STEAP2 gene is mapped to human chromosome 7q21.13. |
| Immunogen【免疫原】 | a 16 amino acid peptide from near the carboxy-terminus of human STEAP2. |
| Biochem/physiol Actions【生化/生理作用】 | The Six-transmembrane epithelial antigen of prostate 2 (STEAP2) being localized in Golgi membrane and cytoplasmic vesicles, may have a critical role in the endocytic pathway. It is highly expressed in prostate carcinomas (PCa) and promotes tumor invasion and migration. Along with STEAP3 and 4, STEAP2 levels are implicated in favoring copper and iron uptake. Studies on targeted STEAP2 knockdown have reported a reduction in PCa progression. |
| Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP4307. |
| Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | predicted mol wt 54 kDa |
| species reactivity | human, mouse |
| technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | Q8NFT2 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... STEAP2(261729) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
