Anti-SYK (Ab-323) antibody produced in rabbit

NA.41

Peptide sequence around aa. 321-325 (N-P-Y-E-P), according to the protein SYK.

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Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

rabbit

100

unconjugated

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

~72 kDa

human

1 mg/mL

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

IgG

(N-P-Y-E-P)

NP_001128524.1

P43405

wet ice

−20℃

human ... SYK(6850)

Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion.

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10 - Combustible liquids

WGK 1