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Anti-Syndecan4 antibody produced in rabbit
产品别名
Anti-Syndecan4 antibody produced in rabbit
amphiglycan
Syndecan-4 precursor
SYND4
Ryudocan core protein
SDC4
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | The SDC-4 (syndecan-4) gene encodes a membrane-spanning proteoglycan which can bear heparan sulfate and chondroitin sulfate chains. Syndecan-4 is predominantly expressed on smooth muscle cells, epithelial cells and cardiomyocytes. The SDC-4 gene is mapped to human chromosome 20q13.12. Anti-Syndecan4 antibody detects endogenous levels of total syndecan-4 protein. |
| Immunogen【免疫原】 | The antiserum was produced against synthesized peptide derived from human Syndecan4. Immunogen Range: 145-194 |
| Biochem/physiol Actions【生化/生理作用】 | Syndecan-4 (SDC-4) is associated with bone development and osteogenesis by regulating fibroblast growth factor-2 (FGF2). SDC-4 gene expression promotes cell division, migration and adhesion. It is essential for wound healing and takes part in inflammation and fibrosis. An abnormal SDC-4 expression is observed in response to stress and metastatic tumor. Growth factors such as FGF2, TNF-α (tumor necrosis factor α) and TGF-β (transforming growth factor β) also tend to alter SDC-4 expression. It is implicated as a biomarker in cardiovascular disease. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 21 kDa |
| species reactivity | mouse, human, rat |
| concentration【浓度】 | ~1 mg/mL |
| technique(s) | ELISA: 1:40000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI accession no.【NCBI登记号】 | P31431 |
| UniProt accession no.【UniProt登记号】 | P31431 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SDC4(6385) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
