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Anti-Tumor Necrosis Factor Soluble Receptor Type II antibody produced in goat

产品编号:3403565
规格:IgG fraction of antiserum, lyophilized powder
包装规格:1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
34035651 MG4730
产品别名

Anti-Tumor Necrosis Factor Soluble Receptor Type II antibody produced in goat

p75TNFR

tumor necrosis factor receptor superfamily member 1B

Etanercept

CD120b antigen

TNF-R2

p75 TNF receptor

TNF sRII

p75TBPII

基本信息
MDL number
MFCD01633483
NACRES
NA.41
General description【一般描述】
TNF RII is a type I transmembrane glycoprotein primarily expressed on hematopoietic cells and is designated TNFRSF1B. TNF RII is a highaffinity receptor for TNF alpha and TNF beta. A soluble form of the receptor generated by proteolytic cleavage functions as a TNF antagonist.
Specificity【特异性】
The antibody detects human TNF sRII and shows no cross-reactivity with recombinant human TNF sRI.
Immunogen【免疫原】
recombinant human TNF soluble receptor II (TNF sRII) expressed in Escherichia coli. The immunogen is the non-glycosylated, N-terminal methionyl form of the naturally-occurring human soluble type II receptor for TNF, minus 53 amino acids from the proline-rich region just exterior to the transmembrane domain.
Application【应用】
Western Blot: 1 ug/mL detects rhs TNF RII at 5 ng/lane under non-reducing conditions
Immunocytochemistry: Concentration of 5-15 ug/ml detects TNF RII in human peripheral blood lymphocytes

Optimal dilutions should be determined by the end user.
Physical form【外形】
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline (pH 7.4) and 5% trehalose.
Other Notes【其他说明】
Protein A or G purified
产品性质
Quality Level【质量水平】
200
biological source【生物来源】
goat
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
IgG fraction of antiserum
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
lyophilized powder
species reactivity
human
technique(s)
immunocytochemistry: 5-15 μg/mL (detects TNF RII in human PBLs)
western blot: 1 μg/mL (detects rhs TNF RII at 5 ng/lane under non-reducing conditions)
UniProt accession no.【UniProt登记号】
P20333
storage temp.【储存温度】
−20℃
Gene Information
human ... TNFRSF1B(7133)
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 1
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