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Anti-Ubiquitin antibody produced in rabbit
产品编号: | 3404008 |
规格: | IgG fraction of antiserum, buffered aqueous solution |
包装规格: | 400 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Ubiquitin antibody produced in rabbit
UBC
Ubiquitin
Polyubiquitin-C
泛素
基本信息
NACRES | NA.41 |
General description【一般描述】 | Ubiquitin, also known as ubiquitin C (UBC), is a globular protein, encoded by the gene mapped to human chromosome 12q24.31. The encoded protein consists of 76 amino acids. |
Immunogen【免疫原】 | a synthetic peptide between 36-66 amino acids of human Ubiquitin, which is in the Ubiquitin-like 1 domain |
Application【应用】 | Anti-ubiquitin antibody produced in rabbit has been used in western blotting. |
Biochem/physiol Actions【生化/生理作用】 | Ubiquitin plays a major role in protein degradation. Ubiquitin-mediated degradation of regulatory proteins has been implicated in the regulation of various processes, such as cell-cycle progression, signal transduction, transcriptional regulation, receptor down-regulation and endocytosis. Aberrations in the ubiquitin-mediated pathways contribute to malignant transformation. |
Physical form【外形】 | Supplied in PBS with 0.09% (W/V) sodium azide |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 77039 Da |
species reactivity | human |
technique(s) | immunofluorescence: 1:10-1:50 immunohistochemistry: 1:50-1:100 western blot: 1:1000 |
UniProt accession no.【UniProt登记号】 | P0CG48 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |