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Anti-XTP3-B antibody produced in rabbit
| 产品编号： | 3406108 |
| 规格： | ~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-XTP3-B antibody produced in rabbit
Anti-XTP3-transactivated protein B
Anti-XTP3TPB
Anti-ERLEC1
Anti-Endoplasmic reticulum lectin 1
Anti-Erlectin 1
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | XTP3-transactivated gene B precursor (XTP3-B), also known as Erlectin is an ER-resident lectin. XTP3-B contains two mannose 6-phosphate receptor homology (MRH) domains in its sequence. The XTP3-B gene is mapped to human chromosome 2p16.2. |
| Application【应用】 | Anti-XTP3-B antibody produced in rabbit has been used in immunoblotting and immunofluorescence. |
| Biochem/physiol Actions【生化/生理作用】 | XTP3-transactivated gene B precursor (XTP3-B), plays a role in endoplasmic-reticulum-associated protein degradation (ERAD) selection and targeting processes. Human XTP3-B associates with the SEL1L/HRD1 ubiquitin ligase complex in the ER membrane and with the ER chaperone BiP, forming an ER quality control scaffold complex. This large complex is involved in identifying and sorting of misfolded glycoproteins and non-glycosylated proteins prior to retrotranslocation into the cytoplasm for degradation. |
| Physical form【外形】 | Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~54 kDa |
| species reactivity | rat, human, mouse |
| packaging【包装】 | antibody small pack of 25 μL |
| concentration【浓度】 | ~1.0 mg/mL |
| technique(s) | indirect immunofluorescence: 2-5 μg/mL using rat NRK cells western blot: 1-2 μg/mL using whole extracts of human G361 and mouse 3T3 cells |
| UniProt accession no.【UniProt登记号】 | Q96DZ1 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ERLEC1(27248) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
