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Anti-Zyxin antibody produced in rabbit
| 产品编号： | 3408792 |
| 规格： | IgG fraction of antiserum, buffered aqueous solution |
| 包装规格： | 200 μL |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
基本信息
| MDL number | MFCD01634364 |
| NACRES | NA.41 |
| General description【一般描述】 | Zyxin (ZYX ), a zinc-binding phosphoprotein of ∼61kDa is located at focal adhesions and along the actin cytoskeleton. It has three LIM domains. This structural protein is located on human chromosome 7q34. |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acid residues 134-150 of human zyxin with N-terminal added cysteine conjugated to KLH. The corresponding sequence differs by one amino acid in mouse. |
| Application【应用】 | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 papers) Anti-Zyxin antibody has been used in fluorescence microscopy. |
| Biochem/physiol Actions【生化/生理作用】 | Zyxin (ZYX ) participates in the modulation of actin assembly at focal adhesions and stress fibers. It also regulates cell adhesion and cell cycle. Overexpression of ZYX is associated with melanoma. Suppression of ZYX prevents cell growth. |
| Physical form【外形】 | 0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。 |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 200 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen 82-84 kDa |
| species reactivity | rat, human, mouse |
| technique(s) | indirect immunofluorescence: 1:100 using Rat1 cells western blot (chemiluminescent): 1:1,000 using whole extract of human HeLa cells western blot (chemiluminescent): 1:2,000 using whole extract of mouse NIH3T3 cells |
| UniProt accession no.【UniProt登记号】 | Q15942 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ZYX(7791) mouse ... Zyx(22793) rat ... Zyx(114636) |
| packaging【包装】 | 200 μL in glass insert |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
