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Arachidonyl trifluoromethyl ketone
产品别名
149301-79-1
Arachidonyl trifluoromethyl ketone
AACOCF3
Arach-CF3
1,1,1-Trifluoromethyl-6,9,12,15-heieicosatetraen-2-one
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C21H31F3O |
Molecular weight | 356.47 |
MDL number | MFCD00236427 |
PubChem Substance ID【PubChem化学物质编号】 | 24890647 |
NACRES | NA.77 |
Application【应用】 | Arachidonyl trifluoromethyl ketone (AACOCF3) has been used as a anandamide degradation inhibitor to study its effects in primary astrocyte cultures. |
Biochem/physiol Actions【生化/生理作用】 | Arachidonyl trifluoromethyl ketone (AACOCF3) plays a role in the inhibition of 12-hydroxyeicosatetraenoic acid (12-HETE) and thromboxane B2 produced by the platelets. Inhibits anandamide hydrolysis in vitro; inhibits phospholipase A2. |
Features and Benefits【特点和优势】 | This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
Caution【注意】 | Hygroscopic, photosensitive, air sensitive |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥97% (NMR) |
form【形式】 | oil |
storage condition【储存条件】 | desiccated protect from light under inert gas |
color【颜色】 | yellow |
solubility【溶解性】 | DMSO: >5 mg/mL |
storage temp.【储存温度】 | −20℃ |
SMILES string | CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)C(F)(F)F |
InChI | 1S/C21H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(25)21(22,23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15- |
InChI key | PLWROONZUDKYKG-DOFZRALJSA-N |
Gene Information | human ... PLA2G1B(5319) |
packaging【包装】 | 5 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |