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β-烟酰胺腺嘌呤二核苷酸 2′-还原磷酸盐 四钠盐
β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt
产品别名
β-烟酰胺腺嘌呤二核苷酸 2′-还原磷酸盐 四钠盐
β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt
β-NADPH
Coenzyme II reduced tetrasodium salt
Triphosphopyridine nucleotide reduced tetrasodium salt
NADPH Na4
2′-NADPH
TPNH2 Na4
Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt
磷酸二氢烟酰胺腺嘌呤二核苷酸 四钠盐
还原型三磷酸吡啶核苷酸 四钠盐
NADPH Na 4
辅酶 II减少 四钠盐
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C21H26N7Na4O17P3 |
Molecular weight | 833.35 |
EC number【EC 号】 | 214-664-6 |
MDL number | MFCD00036263 |
PubChem Substance ID【PubChem化学物质编号】 | 24897841 |
NACRES | NA.51 |
Application【应用】 | β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP). β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt has been used in the Griess reagent assay of culture medium to reduce nitrate to nitrite and in glutathione peroxidase assay. |
Biochem/physiol Actions【生化/生理作用】 | β-烟酰胺腺嘌呤二核苷酸 2′-磷酸盐 (NADP +) 和 β-烟酰胺腺嘌呤二核苷酸 2′-还原磷酸盐 (NADPH) 包含辅酶氧化还原对 (NADP + :NADPH),参与广泛的酶催化氧化还原反应。NADP + /NADPH 氧化还原对促进合成代谢反应中的电子转移,如脂质和胆固醇生物合成和脂肪酰基链的延长。NADP + /NADPH 氧化还原对被用于多种抗氧化机制,在该机制中可防止活性氧化物质积聚。NADPH 在体内通过磷酸戊糖途径 (PPP) 生成 。 |
Preparation Note【制备说明】 | 化学还原 |
Other Notes【其他说明】 | 根据 UV-Vis 测定的 NADPH 含量包装。 |
产品性质
Quality Level【质量水平】 | 200 |
Assay【测定】 | ~95% |
form【形式】 | powder |
packaging【包装】 | vial of 10 mg |
InChI | 1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1 |
InChI key | WYWWVJHQDVCHKF-MPUNMZHWSA-J |