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还原型 β-烟酰胺腺嘌呤二核苷酸 二钠盐
β-Nicotinamide adenine dinucleotide, reduced disodium salt
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3411642 | 15 VIALS | 2030 |
产品别名
606-68-8
还原型 β-烟酰胺腺嘌呤二核苷酸 二钠盐
β-Nicotinamide adenine dinucleotide, reduced disodium salt
Coenzyme I reduced disodium salt
β-NADH
Diphosphopyridine nucleotide reduced disodium salt
β-DPNH
Diphosphopyridine nucleotide reduced 二钠盐
Coenzyme I reduced 二钠盐
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H27N7Na2O14P2 |
| Molecular weight | 709.40 |
| Beilstein | 5230241 |
| EC number【EC 号】 | 210-123-3 |
| MDL number | MFCD00036200 |
| PubChem Substance ID【PubChem化学物质编号】 | 24897788 |
| NACRES | NA.51 |
| General description【一般描述】 | β-Nicotinamide adenine dinucleotide (β-NAD) regulates energy metabolism and immunity. It is a cofactor for mitochondrial deacetylase sirtuin-3 enzyme and modulates inflammasome assembly. β-NAD supresses interleukin-1β levels in monocytic cells in inflammatory syndromes. β-NAD released by neurosecretory cells is a potential neurotransmitter. β-NAD is a vascular mediator in lung endothelial cells and may play a protective role against cytokine mediated inflammation. |
| Application【应用】 | β-Nicotinamide adenine dinucleotide, reduced disodium salt has been used:
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). |
| Biochem/physiol Actions【生化/生理作用】 | 电子供体 |
| Reconstitution【重悬】 | 溶液应新鲜制备并及时使用。 |
| Other Notes【其他说明】 | 根据 UV-Vis 测定的 NADH 含量包装。 这是 NADH 的常见形式；不要与 α 混淆-NADH。 |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ~98% |
| form【形式】 | powder |
| packaging【包装】 | pkg of 0.2 mg (per vial) |
| SMILES string | [Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O |
| InChI | 1S/C21H29N7O14P2.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;/q;2*+1/p-2/t10-,11+,13-,14+,15-,16+,20-,21+;;/m0../s1 |
| InChI key | QRGNQKGQENGQSE-QUWMEQBESA-L |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
