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BRD56491
产品别名
14756-26-4
BRD56491
2-(4-Methylphenyl)-4H-naphtho[1,2-b]pyran-4-one
2-(4-Methylphenyl)-4H-benzo[h]chromen-4-one
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H14O2 |
| Molecular weight | 286.32 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | BRD56491 is a nontoxic enhancer of reactive oxygen species (ROS) that strongly elevates markers of oxidative stress without causing cell death. However, combining BRD56491 with nontoxic doses of the glutathione synthesis inhibitor L-buthionine sulfoximine did lead to cell death in a variety of cancer cell lines. BRD56491 can be used to create a more oxidizing cell state and aid in studies of cancer cell lines resilient to induced increases in ROS levels. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 2 mg/mL, clear (warmed) |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Hazard Statements | H413 |
| Hazard Classifications【危险分类】 | Aquatic Chronic 4 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
