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Bryostatin 2
产品别名
87745-28-6
Bryostatin 2
(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-1,11,21,25-Tetrahydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-
(+)-Bryostatin 2
基本信息
| Empirical Formula【经验(实验)分子式】 | C45H66O16 |
| Molecular weight | 863.00 |
| Biochem/physiol Actions【生化/生理作用】 | Bryostatin 2 is potent protein kinase C activator (Ki = 5.9 nM) and an antagonist to phorbol ester tumor promoter 12-0-tetradecanoylphorbol-13-acetate (TPA). Bryostatin 2 exhibits antineoplastic activity against the murine P388 lymphocytic leukemia and human U937 cells. |
产品性质
| biological source【生物来源】 | Bugula neritina (sponge) |
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | film |
| color【颜色】 | colorless to light yellow |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C45H66O16/c1-9-10-11-12-13-14-37(49)59-41-29(21-39(51)56-8)20-32-24-35(27(2)46)58-40(52)23-30(47)22-33-25-36(48)43(5,6)44(53,60-33)26-34-18-28(19-38(50)55-7)17-31(57-34)15-16-42(3,4)45(41,54)61-32/h11-16,19,21,27,30-36,41,46-48,53-54H,9-10,17-18,20,22-26H2,1-8H3/b12-11+,14-13+,16-15+,28-19-,29-21+/t27-,30-,31?,32?,33-,34+,35-,36+,41+,44+,45-/m1/s1 |
| InChI key | LIPGUSBNMQRYNL-WZYRAJGLSA-N |
| packaging【包装】 | 10 μg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
