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Bis(NHS)PEG5

产品编号:3420596
包装规格:100 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3420596100 MG4310
产品别名

Bis(NHS)PEG5

Bis-N-succinimidyl-(pentaethylene glycol) ester

Bis-succinimide ester-activated PEG compound

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C22H32N2O13
Molecular weight
532.50
NACRES
NA.22
General description【一般描述】
By contrast to typical PEG reagents that contain heterogeneous mixtures of different PEG chain lengths, this PEG reagent is a homogeneous compound of defined molecular weight and spacer arm length, providing greater precision in optimization and characterization of crosslinking applications. Homobifunctional crosslinkers containing N-hydroxysuccinimide (NHS) esters are often used for low-resolution 3-D studies of protein structure and protein interaction analysis.
Features and Benefits【特点和优势】
  • Reactive groups: NHS ester (both ends)
  • Reactive towards: amino groups (primary amines)
  • NHS esters react with—NH2 groups at pH 7-9, forming stable amide bonds
  • Water-soluble; compare to non-pegylated BS3 (also soluble) and DSS (water-insoluble)
  • Membrane-impermeable, allowing for cell surface labeling
  • Irreversibly crosslink proteins or peptides by flexible PEG spacer arms
  • Polyethylene glycol spacer arms help maintain conjugate solubility
  • Pure compound with defined structure and molecular weight, ensuring reproducible protein-modification effects
  • PEG spacer provides unique advantages, including increased stability, reduced tendency toward aggregation and reduced immunogenicity
  • Ideal for small molecule or peptide conjugations
Caution【注意】
This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.
产品性质
form【形式】
liquid
Quality Level【质量水平】
100
mol wt【分子量】
532.5
reaction suitability
reagent type: cross-linking reagent
storage condition【储存条件】
desiccated
solubility【溶解性】
water: soluble
shipped in【运输】
ambient
storage temp.【储存温度】
−20℃
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 3
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