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BTZO-1
产品别名
99420-15-2
BTZO-1
2-Pyridin-2-yl-4H-1,3-benzothiazin-4-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H8N2OS |
| Molecular weight | 240.28 |
| MDL number | MFCD19690951 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825172 |
| NACRES | NA.77 |
| Application【应用】 | BTZO-1 may be used in ARE-mediated gene expression studies. |
| Biochem/physiol Actions【生化/生理作用】 | BTZO-1 is a suppressor of cardiomyocyte apoptosis presumably by activation of antioxidant response element (ARE)-mediated gene expression. BTZO-1 binds to the macrophage migration inhibitory factor (MIF) that is required to activate the glutathione S-transferase Ya subunit (GST Ya) gene ARE. |
| Features and Benefits【特点和优势】 | This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to tan |
| solubility【溶解性】 | DMSO: ≥7 mg/mL |
| originator【创始人】 | Takeda |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C1N=C(Sc2ccccc12)c3ccccn3 |
| InChI | 1S/C13H8N2OS/c16-12-9-5-1-2-7-11(9)17-13(15-12)10-6-3-4-8-14-10/h1-8H |
| InChI key | GBAKVEWPYUIGHN-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
