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CGP36742
产品别名
123690-78-8
CGP36742
SGS 742
P-(3-Aminopropyl)-P-butyl-phosphinic acid
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C7H18NO2P |
Molecular weight | 179.20 |
MDL number | MFCD00882735 |
PubChem Substance ID【PubChem化学物质编号】 | 329825430 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | CGP36742 was the first orally active GABAB-selective antagonist. The IC50 for blocking GABAergic transmission is 36 μM. Oral administration of CGP36742 in rats blocks baclofen-induced neuronal depression, and reduces learning deficit and passive avoidance in an olfactory bulbectomy depression model. |
Features and Benefits【特点和优势】 | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥97% (NMR) |
form【形式】 | powder |
storage condition【储存条件】 | desiccated |
color【颜色】 | white to beige |
solubility【溶解性】 | H2O: 10 mg/mL (clear solution, warmed) |
storage temp.【储存温度】 | room temp |
SMILES string | CCCCP(O)(=O)CCCN |
InChI | 1S/C7H18NO2P/c1-2-3-6-11(9,10)7-4-5-8/h2-8H2,1H3,(H,9,10) |
InChI key | ONNMDRQRSGKZCN-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 - H319 |
Precautionary Statements | P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 |
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |