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CGP52432

产品编号:3424624
规格:≥98% (HPLC)
CAS NO:139667-74-6
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
34246245 MG1900
342462425 MG5250
产品别名

139667-74-6

CGP52432

[3-[[(3,4-Dichlorophenyl)methyl]amino]propyl](diethoxymethyl)-phosphinic acid

基本信息
Empirical Formula【经验(实验)分子式】
C15H24Cl2NO4P
Molecular weight
384.24
NACRES
NA.77
Application【应用】
CGP52432 has been used as a γ-aminobutyric acid B (GABAB) antagonist:
  • to study its effects on the simulation of the onset of status epilepticus (SE) in mice
  • for voltage-clamp recording in mice neurons
  • to study its effects on the GABAB receptor-mediated neurotransmission in guinea pig hippocampus

Biochem/physiol Actions【生化/生理作用】
CGP52432 participates in inhibiting the glycine overflow in the hippocampus.
CGP52432 is a very potent antagonist of GABAB receptors. (IC50 = 85 nM).
Features and Benefits【特点和优势】
This compound is featured on the GABAB Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Other Notes【其他说明】
注意:不要冻存。
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
storage condition【储存条件】
desiccated
color【颜色】
white to beige
solubility【溶解性】
H2O: 1 mg/mL, clear (warmed)
storage temp.【储存温度】
2-8℃
InChI
1S/C15H24Cl2NO4P/c1-3-21-15(22-4-2)23(19,20)9-5-8-18-11-12-6-7-13(16)14(17)10-12/h6-7,10,15,18H,3-5,8-9,11H2,1-2H3,(H,19,20)
InChI key
GJZVQXWEIYRHBE-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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