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Chlorisondamine diiodide

产品编号:3425052
规格:≥98% (HPLC), white, solid
CAS NO:96750-66-2
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
342505210 MG1920
342505250 MG6610
产品别名

96750-66-2

Chlorisondamine diiodide

4,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl]-2H-isoindolium diiodide

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C14H20Cl4I2N2
Molecular weight
611.94
MDL number
MFCD01074794
PubChem Substance ID【PubChem化学物质编号】
24724443
NACRES
NA.77
Application【应用】
Chlorisondamine diiodide has been used:
  • as a nicotinic receptor antagonist to test its effect on trinitrobenzene sulfonic acid (TNBS)-induced colitis
  • as an irreversible nicotinic acetylcholine(nAChR) blocker to pre-treat brain samples to test its effect on cytochrome P450 2B (CYP2B) induction
  • as a ganglionic blocker to test its effect on regulating corticosterone levels in rat with chronic stress

Biochem/physiol Actions【生化/生理作用】
Chlorisondamine diiodide mediates ganglionic and central blockade.
Irreversible, long-lasting nicotinic acetylcholine receptor antagonist.
Features and Benefits【特点和优势】
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
产品性质
Assay【测定】
≥98% (HPLC)
form【形式】
solid
storage condition【储存条件】
protect from light
color【颜色】
white
solubility【溶解性】
H2O: ≥2 mg/mL
DMSO: >20 mg/mL
storage temp.【储存温度】
2-8℃
SMILES string
[I-].[I-].C[N+](C)(C)CC[N+]1(C)Cc2c(Cl)c(Cl)c(Cl)c(Cl)c2C1
InChI
1S/C14H20Cl4N2.2HI/c1-19(2,3)5-6-20(4)7-9-10(8-20)12(16)14(18)13(17)11(9)15;;/h5-8H2,1-4H3;2*1H/q+2;;/p-2
InChI key
FPNVAOZHQUJJJQ-UHFFFAOYSA-L
packaging【包装】
10, 50 mg in glass bottle
安全信息
Pictograms【象形图】
GHS07,GHS09
Signal word【警示用语:】
Warning
Hazard Statements
H302 - H400
Precautionary Statements
P273 - P301 + P312 + P330
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Aquatic Acute 1
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 2
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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