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CID755673

产品编号:3425906
规格:≥98% (HPLC), powder
CAS NO:521937-07-5
包装规格:5 MG,25 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
34259065 MG1660
342590625 MG6090
产品别名

521937-07-5

CID755673

7-Hydroxy-2,3,4,5-tetrahydro-1H-benzofuro[2,3-c]azepin-1-one

2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C12H11NO3
Molecular weight
217.22
MDL number
MFCD03828155
PubChem Substance ID【PubChem化学物质编号】
329825080
NACRES
NA.77
Application【应用】
CID755673 was used to study the role of PKD in dendrite retraction in mouse Purkinje cells.
Biochem/physiol Actions【生化/生理作用】
CID755673 is a cell-permeable, potent and selective inhibitor of all three protein kinase D (PKD) isoforms PKD1 (PKCμ), PKD2, and PKD3 (PKCν). CID755673 is not competitive with ATP.
CID755673 was not suitable to inhibit PKD in Swiss 3T3 cells as it utilizes PKD-dependent pathway to enhance the mitogenic signaling triggered by EGF, phorbol esters and bombesin. It should, therefore, be used with caution.
Features and Benefits【特点和优势】
This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to tan
solubility【溶解性】
DMSO: ≥15 mg/mL
storage temp.【储存温度】
2-8℃
SMILES string
Oc1ccc2oc3C(=O)NCCCc3c2c1
InChI
1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)
InChI key
AACFPJSJOWQNBN-UHFFFAOYSA-N
packaging【包装】
5, 25 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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