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Ciglitizone
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3425913 | 5 MG | 4330 |
产品别名
74772-77-3
Ciglitizone
(±)-5-[4-(1-Methylcyclohexylmethoxy)benzyl]thiazolidine-2,4-dione
Ciglitazone
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H23NO3S |
| Molecular weight | 333.45 |
| MDL number | MFCD00865499 |
| PubChem Substance ID【PubChem化学物质编号】 | 24892661 |
| NACRES | NA.77 |
| Application【应用】 | Ciglitizone has been used as a proliferator-activated receptor γ (PPARγ) agonist:
It also may be used to study its effects on cell cycle and apoptosis in monocytic cells. |
| Biochem/physiol Actions【生化/生理作用】 | Ciglitizone belongs to the class of thiazolidinediones and is a peroxisome proliferator-activated receptor γ (PPARγ) agonist. It exhibits anti-diabetic activity. Ciglitizone has the potential to treat tumor necrosis factor α (TNFα)-related apoptosis-inducing ligand (TRAIL)-refractory high-grade urothelial cancers. |
| Features and Benefits【特点和优势】 | This compound was developed by Takeda. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| originator【创始人】 | Takeda |
| SMILES string | CC1(CCCCC1)COc2ccc(CC3SC(=O)NC3=O)cc2 |
| InChI | 1S/C18H23NO3S/c1-18(9-3-2-4-10-18)12-22-14-7-5-13(6-8-14)11-15-16(20)19-17(21)23-15/h5-8,15H,2-4,9-12H2,1H3,(H,19,20,21) |
| InChI key | YZFWTZACSRHJQD-UHFFFAOYSA-N |
| Gene Information | human ... PPARG(5468) mouse ... Pparg(19016) |
| packaging【包装】 | 5 mg in glass insert |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
