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基本信息
| NACRES | NA.41 | ||||
| General description【一般描述】 | Glucose transporter membrane 3 (GLUT3) is known as a solute carrier family 2 (facilitated glucose transporter) member 3 and represents a membrane bound glucose transporter. In one study scientists, using immunoprecipitation and western blot technologies, detected GLUT3 expression in spermatozoa of testis and brain but not in other types of tissue. In-house research via immunohistochemistry confirmed GLUT3 expression in testis/spermatozoa, but no GLUT3 was detected in brain. In a study conducted by Howitt BE et. al. anti-GLUT3 demonstrated membranous staining of seminoma cells in 44 cases (65%) of total 67 specimens. In addition, anti-GLUT3 labeled embryonal carcinoma (20/20) and yolk sac tumor (8/8) with 100% sensitivity.GLUT3 is not expressed in non-germ cell tumors such as leydig cell tumor and adenomatoid tumor.Spermatocytic seminoma, choriocarcinoma, and immature teratoma are also negative for GLUT3. Therefore, anti-GLUT3 is a very useful IHC marker to include in a panel for identification of germ cell tumors. | ||||
| Quality【质量】 |
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| Linkage【联系】 | GLUT3 Positive Control Slides, Product No. 413S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). | ||||
| Physical form【外形】 | Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide | ||||
| Preparation Note【制备说明】 | Download the IFU specific to your product lot and format Note: This requires a keycode which can be found on your packaging or product label. Download the latest released IFU Note: This IFU may not apply to your specific product lot. | ||||
| Other Notes【其他说明】 | For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com | ||||
| Legal Information【法律信息】 | Cell Marque is a trademark of sigma-aldrich Co. LLC |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 500 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | Ig fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| description【描述】 | For In Vitro Diagnostic Use in Select Regions (See Chart) |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| packaging【包装】 | vial of 0.1 mL concentrate (413A-14) vial of 0.5 mL concentrate (413A-15) bottle of 1.0 mL predilute (413A-17) vial of 1.0 mL concentrate (413A-16) bottle of 7.0 mL predilute (413A-18) |
| manufacturer/tradename | Cell Marque™ |
| technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 |
| control【控制】 | embryonal carcinoma, yolk sac tumor |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| visualization【可视化】 | membranous |
