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TrueGel3D 水凝胶试剂盒
TrueGel3D Hydrogel Kits
| 产品编号： | 4057963 |
| 规格： | FAST-PVA, CD cell-degradable crosslinker |
| 包装规格： | 1 KIT |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
TrueGel3D 水凝胶试剂盒
TrueGel3D Hydrogel Kits
产品性质
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
基本信息
| General description【一般描述】 | The gel is formed by stable thioether bonds between maleimide groups of PVA (FAST-PVA) and thiol groups on CD cell-degradable crosslinker. Malemide-functionalized PVA is specifically used to decrease the time for gel formation. The PVA polymer does not have cell attachment sites, but it can be customized to conjugate RGD peptide using TrueGel3D RGD peptide (TRUERGD-1EA) prior to the crosslinking step. The CD cell-degradable crosslinker is composed of matrix metalloprotease (MMP)-cleavable peptide (Pro-Leu-Gly-Leu-Trp-Ala), which allows cells to spread and migrate by secreting matrix metalloproteases (MMP1, MMP3, MMP7 and MMP9). |
| Application【应用】 | TRUE4-1KT is used for cell migration studies of amoeboid cells including neutrophils, dendritic cells and lymphocytes. It has been preferred to use PVA-based gels over dextran-based gels for long-term culture of cells producing carbohydrate degrading enzymes. |
| Features and Benefits【特点和优势】 |
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| Components【组分】 | TRUE4-1KT contains FAST-PVA polymer solution in phosphate buffer and lyophilized CD cell-degradable crosslinker with reconstitution buffer, TrueGel3D thioglycerol and water. |
| Caution【注意】 | Avoid prolong exposure of CD cell-degradable crosslinker to air and store FAST-PVA in small portions to avoid frequent freeze-thaw cycles. |
安全信息
| Pictograms【象形图】 | GHS05 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H290 |
| Precautionary Statements | P234 - P390 |
| Hazard Classifications【危险分类】 | Met. Corr. 1 |
| Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
