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WHI-P180
| 产品编号： | 4061769 |
| 规格： | A potent inhibitor of lgE-mediated mast cell responses to allergens in vitro and in vivo. |
| CAS NO： | 211555-08-7 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4061769 | 1 MG | 3240 |
产品别名
211555-08-7
WHI-P180
4-(3'-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H15N3O3 |
| Molecular weight | 297.31 |
| General description【一般描述】 | A potent inhibitor of IgE-mediated mast cell responses to allergens in vitro and in vivo. Also inhibits cyclin-dependent kinase 2 (Cdk2; IC50 = 1 µM) by blocking the ATP site. A potent inhibitor of lgE-mediated mast cell responses to allergens in vitro and in vivo. Also inhibits cyclin-dependent kinase 2 (Cdk2; IC50 = 1 µM) by blocking the ATP site. |
| Biochem/physiol Actions【生化/生理作用】 | Target IC50: 1 µM for Cdk2 Primary Target Cdk2 Product does not compete with ATP. Reversible: no Cell permeable: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |
| Other Notes【其他说明】 | Shewchuk, L., et al. 2000. J. Med. Chem. 43, 133. Chen, C.L., et al. 1999. Pharm. Res. 16, 117. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | pale yellow |
| solubility【溶解性】 | DMSO: 50 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 1 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
