您的位置：首页 > 产品中心 > 钙蛋白酶抑制剂 IV-Calbiochem
钙蛋白酶抑制剂 IV-Calbiochem
Calpain Inhibitor IV-Calbiochem
| 产品编号： | 4061799 |
| 规格： | The Calpain Inhibitor IV controls the biological activity of Calpain. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
钙蛋白酶抑制剂 IV-Calbiochem
Calpain Inhibitor IV-Calbiochem
Z-LLY-FMK
基本信息
| Empirical Formula【经验(实验)分子式】 | C30H40FN3O6 |
| Molecular weight | 557.65 |
| General description【一般描述】 | A potent, cell-permeable and irreversible inhibitor of calpain II (k2 = 28,900 M-1s-1). Also acts as an inhibitor of cathepsin L (k2 = 680,000 M-1s-1). A potent, cell-permeable, and irreversible inhibitor of calpain II (k2 = 28,900 M-1s-1). Also acts as an inhibitor of cathepsin L (k2 = 680,000 M-1s-1). |
| Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Cell permeable: yes k₂ = 28,900 M⁻¹s⁻¹ in the inhibition of calpain II; k2 = 680,000 M⁻¹s⁻¹ in the inhibition of cathepsin L Reversible: no Primary Target calpain 2 |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Sequence【序列】 | Z-Leu-Leu-Tyr-CH₂F |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |
| Analysis Note【分析说明】 | single spot by TLC |
| Other Notes【其他说明】 | Dutt, P., et al. 1998. FEBS Lett. 436, 367. Angliker, H., et al. 1992. J. Med. Chem. 35, 216. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated |
| color【颜色】 | white to pale yellow |
| solubility【溶解性】 | DMSO: 25 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 1 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
