GW1929-CAS 196808-24-9-Calbiochem

C₃₀H₂₉N₃O₄

495.57

A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC₅₀ = 13 nM for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays).
A potent, tyrosine-based peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC₅₀ = 13 nM for murine PPARγ and 6.2 nM for human PPARγ in cell-based transactivation assays).

Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Peroxisome proliferator-activated receptor γ (PPARγ) agonist
EC50 = 13 nM as peroxisome proliferator-activated receptor γ (PPARγ) agonist for murine receptor and 6.2 nM for human receptor in cell-based transactivation assays

Toxicity: Standard Handling (A)

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Han, S., et al. 2004. Clin. Cancer Res.10, 1911.
Willson, T.M., et al. 2000. J. Med. Chem.43, 527.
Brown, K.K., et al. 1999. Diabetes48, 1415.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥97% (NMR)

crystalline solid

Calbiochem^®

OK to freeze
protect from light

yellow

DMSO: 100 mg/mL

ambient

−20℃

1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18,27,32H,19-21H2,1H3,(H,35,36)/t27-/m0/s1

QTQMRBZOBKYXCG-MHZLTWQESA-N

1 mg in Plastic ampoule
Packaged under inert gas

11 - Combustible Solids

WGK 1