Thrombin, Plasminogen-Free, Bovine

100

lyophilized

≥1000 NIH units/mg protein

Calbiochem^®

OK to freeze
desiccated

water: 1 mg/mL

Plasminogen, none detected (by rocket IEP)

ambient

−20℃

1 ku in Plastic ampoule

Native, bovine thrombin. Key enzyme that activates factor XIII and converts fibronogen into fibrin. Note: 1 KU = 1000 units.
Native, bovine thrombin. Key enzyme that activates factor XIII and converts fibronogen into fibrin. Serine protease formed in the plasma during the coagulation process by activation of prothrombin by a complex of Factor Xa, Factor Va, phospholipid, and Ca²⁺. Thrombin cleaves Arg-Gly bonds in specific sequences only. The best characterized activity of thrombin is the conversion of fibrinogen to fibrin in the clotting process. Inhibited by AEBSF (Cat. No. 101500) Antithrombin (Cat. No. 169756), PMSF (Cat. No. 52332), and TLCK (Cat. No. 616382). Note: 1 KU = 1000 units.

Toxicity: Harmful (C)

One unit is determined by comparison with a standard curve prepared using the Bureau of Biologics standard thrombin.

Lyophilized from 200 mM NaCl, 50 mM sodium citrate, 0.1% PEG-8000, pH 6.5.

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 6 months at -70°C.

Complete activation from homogeneous bovine prothrombin by SDS-PAGE

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

GHS07,GHS08

Danger

H315 - H319 - H334 - H335

P261 - P264 - P271 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Respiratory system

11 - Combustible Solids

WGK 1