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来自肝脏的微粒体，合并
Microsomes from Liver, Pooled
产品别名
来自肝脏的微粒体，合并
Microsomes from Liver, Pooled
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | Monkey (Cynomolgus spp.) |
| Assay【测定】 | ~10 mg per vial |
| form【形式】 | liquid |
| Specific Activity | ≥5000 units/mg protein |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
基本信息
| Application【应用】 | Microsomes from Liver, Pooled has been used to measure the in vitro stabilities of the prodrugs. It has also been used in microsomal incubation to generate BTX-3 metabolites to serve as references for liquid chromatography with tandem mass spectrometry (LC-MS/MS) analyses of urine. |
| Biochem/physiol Actions【生化/生理作用】 | Microsomal cytochrome P450 proteins can catalyze the transfer of a single oxygen atom to endogenous and exogenous compounds, like steroids and phenobarbital, meant for excretion and detoxification. 肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶(包括细胞色素 P-450)的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。 |
| Unit Definition【单位定义】 | One unit will produce 1.0 picomole of 6 beta-hydroxytestosterone per minute at pH 7.4 at 37 deg C. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
