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(6-Bromohexyl)triphenylphosphonium bromide
产品别名
83152-22-1
(6-Bromohexyl)triphenylphosphonium bromide
Mitochondria-targeting probe building block
Phosphonium lipocation tag
Bromohexane TPP mitochondrial tag
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C24H27Br2P |
| Molecular weight | 506.25 |
| Application【应用】 | Mitochondria perform several functions in the cell, and dysfunction has been implicated in various organ systems and disease states, including neurodegenerative disorders and cancers. The targeting of small molecules to the mitochondria can help to probe and better understand this relationship. This bromohexane triphenylphosphine (TPP) tag is conjugated to small molecules to localize them to the mitochondria in cells where the TPP cations facilitate both cellular uptake and accumulation in the mitochondria. |
| Other Notes【其他说明】 | Targeting lipophilic cations to mitochondria Photoswitchable polyfluorophores based on perylenemonoimide-dithienylethene conjugates as super-resolution MitoTrackers |
产品性质
| Assay【测定】 | ≥95% |
| form【形式】 | solid |
| reaction suitability | reagent type: ligand |
| functional group【官能团】 | phosphine |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | BrCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br] |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
