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1-desoxymethylsphinganine
产品编号: | 4064235 |
规格: | 1-desoxymethylsphinganine (m17:0), powder |
CAS NO: | 1219484-98-6 |
包装规格: | 1 MG |
产品类别: | 进口试剂 |
品牌: | Avanti |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4064235 | 1 MG | 3150 |
产品别名
1219484-98-6
1-desoxymethylsphinganine
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C17H37NO |
Molecular weight | 271.48 |
General description【一般描述】 | 1-desoxymethylsphinganine is synthesized by the condensation of alanine with palmitoyl-CoA. |
Application【应用】 | 1-desoxymethylsphinganine is suitable for use for testing its cytotoxic effects on primary neuron-glia cultures. It is also suitable for use as a neurotoxic agent in human CD8+ T cells. In hereditary sensory and autonomic neuropathy type I, mutations in serine palmitoyltransferase long chain base subunit 1 resulting in altered substrate specificity and accumulation of 1. |
Biochem/physiol Actions【生化/生理作用】 | 1-desoxymethylsphinganine is neurotoxic towards CD8+ T cells and inhibits cytokine production. However, it is not cytotoxic to dopaminergic neurons. |
产品性质
form【形式】 | powder |
manufacturer/tradename | Avanti Polar Lipids 860473P |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
SMILES string | NC[C@]([H])(O)CCCCCCCCCCCCCCC |
packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860473P-1mg) |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |