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16:0-16 Doxyl PC

产品编号:4064319
规格:1-palmitoyl-2-stearoyl-(16-doxyl)-sn-glycero-3-phosphocholine, chloroform
CAS NO:216491-65-5
包装规格:1 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40643191 MG7050
产品别名

216491-65-5

16:0-16 Doxyl PC

基本信息
Empirical Formula【经验(实验)分子式】
C46H90N2O10P
Molecular weight
862.19
NACRES
NA.25
General description【一般描述】
1-palmitoyl-2-stearoyl-(16-doxyl)-sn-glycero-3-phosphocholine (16:0-16 Doxyl PC) is a spin labelled phospholipid.
Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.
Application【应用】
1-palmitoyl-2-stearoyl-(16-doxyl)-sn-glycero-3-phosphocholine (16:0-16 Doxyl PC) may be used:
  • in bilayers or membranes to study the distribution of the lipid-attached doxyl electron paramagnetic resonance (EPR) spin label
  • as spin-labelled lipid in multilamellar vesicles (MLVs) to measure membrane fluidity
  • as a spin-labeled deep quencher in small unilamellar vesicles (SUVs) for nitroxide lipid quenching experiments

Preparation Note【制备说明】
Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.
产品性质
Assay【测定】
>99% (TLC)
manufacturer/tradename
Avanti Polar Lipids 810604C
concentration【浓度】
1 mg/mL (810604C-1mg)
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
packaging【包装】
5 mL Clear Glass Sealed Ampule (810604C-1mg)
安全信息
Pictograms【象形图】
GHS06,GHS08
Signal word【警示用语:】
Danger
Hazard Statements
H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412
Precautionary Statements
P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
Hazard Classifications【危险分类】
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
Target Organs【靶器官】
Central nervous system
Storage Class Code【储存分类代码】
6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 3
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