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22(R)-hydroxycholesterol-d7

产品编号:4064564
规格:cholest-5-ene-3β,22(R)-diol-d7, powder
CAS NO:1246302-93-1
包装规格:1 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40645641 MG8830
产品别名

1246302-93-1

22(R)-hydroxycholesterol-d7

25,26,26,26,27,27,27-heptadeuterocholest-5-ene-3β,22R-diol

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C27H39O2D7
Molecular weight
409.70
NACRES
NA.25
General description【一般描述】
22(R)-hydroxycholesterol is a diastereomer of 22(S)-hydroxycholesterol. It is present in the neonate brain. 22(R)-hydroxycholesterol-d7 is a deuterated form of 22(R)-hydroxycholesterol.
Biochem/physiol Actions【生化/生理作用】
22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand and is a key for the receptor activation.. 22(R)-HC promotes mesenchymal stem cell osteogenesis along with other oxysterols. It also regulates cholesterol homeostasis and suppresses prostate tumor progression. Low levels of 22(R)-HC is observed in Alzheimer′s disease and may be implicated in neuroinflammation and neurodegenerative diseases.
产品性质
Assay【测定】
>99% (TLC)
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 700052P
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
packaging【包装】
5 mL Amber Glass Screw Cap Vial (700052P-1mg)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
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