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人 β-2 微球蛋白 ELISA 试剂盒
Human β-2 Microglobulin ELISA Kit
产品编号: | 4067165 |
规格: | for serum, plasma, cell culture supernatant and urine |
包装规格: | 1 KIT |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
人 β-2 微球蛋白 ELISA 试剂盒
Human β-2 Microglobulin ELISA Kit
b2m
产品性质
species reactivity | human |
packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
technique(s) | ELISA: suitable capture ELISA: suitable |
input | sample type serum sample type urine sample type plasma sample type cell culture supernatant(s) |
assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 6 pg/mL standard curve range: 15.6-1000 pg/mL |
Detection Method | colorimetric |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... B2M(567) |
基本信息
General description【一般描述】 | The Human BDNF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human BDNF in serum, plasma, cell culture supernatants and urine. β2-microglobulin (B2M) is a non-glycosylated polypeptide composed of 99 amino acids. It is present on the surface of all nucleated cells. The protein is characterized with a single polypeptide chain, which is linked noncovalently to major histocompatibility complex (MHC) class I cell surface antigen. The gene coding for B2M is mapped to human chromosome 15q. |
Immunogen【免疫原】 | Recombinant Human β-2-Microglobulin |
Application【应用】 | 请参考Protocol了解详情。 |
Biochem/physiol Actions【生化/生理作用】 | β2-microglobulin (B2M) plays a vital role in cell survival, proliferation and metastasis in various types of cancer. Elevated concentration of β-2-microglobulin (B2M) can be considered as a prognostic marker for hemophagocytic lymphohistiocytosis (HLH). Elevated concentration of circulating B2M, due to renal dysfunction and long term hemodialysis, leads to dialysis-related amyloidosis. Overexpression of serum B2M is observed in hepatitis C virus (HCV) related chronic liver diseases, therefore it might act as a potential marker for the HCV disease progression towards cirrhosis and carcinoma. Missense mutation in the B2M gene results in familial hypercatabolic hypoproteinemia (FHH). |
Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
Components【组分】 | 组份可单独销售 RABELADB ELISA 5X Assay/Sample Diluent Buffer B (Item E1) RABELADC ELISA 1X Assay/Sample Diluent Buffer C (Item L) RABSTOP3 ELISA Stop Solution (Item I) RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H) RABWASH4 20X Wash Buffer (Item B) |
安全信息
Pictograms【象形图】 | GHS05 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H290 |
Precautionary Statements | P234 - P390 |
Hazard Classifications【危险分类】 | Met. Corr. 1 |
Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
WGK | WGK 3 |