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Human Osteopontin ELISA Kit
| 产品编号： | 4067429 |
| 规格： | for serum, plasma, cell culture supernatant and urine |
| 包装规格： | 1 KIT |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Human Osteopontin ELISA Kit
OPN
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | The Human OPN ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human OPN in serum, plasma, cell culture supernatants and urine. |
| Immunogen【免疫原】 | Recombinant Human OPN |
| Application【应用】 | For research use only. Not for use in diagnostic procedures. Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA) Human Osteopontin ELISA Kit has been used in the quantification of serum osteopontin (OPN) in human blood samples. |
| Biochem/physiol Actions【生化/生理作用】 | Osteopontin (OPN) is a secreted glycoprotein and is assumed to be associated with various cellular processes such as adhesion, migration, and biomineralization in diverse tissues. Osteopontin acts as a ligand to αvβ3 integrin and possibly other receptors. In addition to its involvement in mineralized matrix formation, osteopontin can also function as a cytokine that stimulates the release of IFNγ (interferon γ) and IL-12 (interleukin 12), while inhibiting the production of IL-10. Osteopontin is involved in inflammation and also regulates immunity against infectious diseases. It also co-stimulates T cell proliferation. Osteopontin has proinflammatory functions and is associated with multiple sclerosis. It participates in inflammation in Crohn′s Disease. Osteopontin plays a crucial role in bone remodelling and retards ectopic calcification by inhibiting the formation of hydroxyapatite. OPN is thought to prevent renal stone formation by suppressing nucleation, growth and aggregation of calcium oxalate crystals. |
| Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
| Components【组分】 | 组份可单独销售 RABELADE ELISA 5X Assay/Sample Diluent Buffer E (Item E2) RABSTOP3 ELISA Stop Solution (Item I) RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H) RABWASH4 20X Wash Buffer (Item B) |
产品性质
| species reactivity | human |
| packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable capture ELISA: suitable |
| input | sample type serum sample type cell culture supernatant(s) sample type plasma sample type urine |
| assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 50 pg/mL standard curve range: 74.07-18000 pg/mL |
| Detection Method | colorimetric |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... SPP1(6696) |
安全信息
| Pictograms【象形图】 | GHS05 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H290 |
| Precautionary Statements | P234 - P390 |
| Hazard Classifications【危险分类】 | Met. Corr. 1 |
| Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
