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4β-hydroxycholesterol-d7

产品编号:4069952
规格:cholest-5-ene-3,4-diol-d7, powder
CAS NO:1246302-80-6
包装规格:1 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40699521 MG4220
产品别名

1246302-80-6

4β-hydroxycholesterol-d7

cholest-5-ene-3b,4b-diol(d7)

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C27H39O2D7
Molecular weight
409.70
NACRES
NA.25
General description【一般描述】
4β-hydroxycholesterol (4β-HC) is a catabolic product of cholesterol metabolism mediated by the enzyme cytochrome P450 family 3 subfamily A member 4 (CYP3A4). 4β-hydroxycholesterol-d7 is the deuterated form of 4β-hydroxycholesterol.
Application【应用】
4β-hydroxycholesterol-d7 has been used:
  • as an internal standard to spike plasma samples ultra-high-pressure liquid,chromatography–tandem mass spectrometry (UHPLC-MS/MS) analysis
  • to spike serum samples for mass spectrometry measurements
  • as an internal standard for the quantification of human colon biopsies samples using HPLC-MS

Biochem/physiol Actions【生化/生理作用】
4β-hydroxycholesterol (4β-HC) may function as a liver X receptor ligand. The levels of 4β-HC are elevated in dextran sulfate induced colitis along with other oxysterols and it may promote colon inflammation.
产品性质
Assay【测定】
>99% (TLC)
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 700042P
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
packaging【包装】
5 mL Amber Glass Screw Cap Vial (700042P-1mg)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
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