Human Cystatin C ELISA Kit

NA.32

The Human Cystatin C ELISA (enzyme-linked immunosorbent assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human cystatin C in serum, plasma, cell culture supernatants and urine.

Recombinant Human CystatinC

请参考Protocol了解详情。

Cystatin C (CysC) is released by all nucleated cells. Abnormal thyroid function, immunosuppressive therapy and systemic inflammation alter the levels of CysC. Mutation in the gene encoding CysC causes hereditary cystatin C amyloid angiopathy, which is a consequence of amyloid deposits containing the CysC variant in the brain.
Cystatin-C precursor (CST3) is an inhibitor of lysosomal cysteine proteases and several cathepsins like cathepsin S, a lysosomal enzyme. It has been shown that CST3 is a marker of glomerular filtration and diabetic kidney disease. In the presence of pathological conditions, it forms amyloid fibrils in brain arteries. Mutations in the gene encoding CST3 have been shown to be associated with a form of amyloidosis and age-related macular degeneration.

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组份可单独销售
RABELADE ELISA 5X Assay/Sample Diluent Buffer E (Item E2)
RABSTOP3 ELISA Stop Solution (Item I)
RABTMB3 ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
RABWASH4 20X Wash Buffer (Item B)

human

kit of 96 wells (12 strips x 8 wells)

ELISA: suitable
capture ELISA: suitable

sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type serum

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 300 pg/mL
standard curve range: 0.313-20 ng/mL

colorimetric

wet ice

−20℃

human ... CST3(1471)

GHS05

Warning

H290

P234 - P390

Met. Corr. 1

8A - Combustible, corrosive hazardous materials

WGK 3