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LightOxTM14
产品别名
198696-03-6
LightOxTM14
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C23H25NO2 |
Molecular weight | 347.45 |
Application【应用】 | Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy. |
Biochem/physiol Actions【生化/生理作用】 | Strong ligand for retinoic acid receptor proteins |
Features and Benefits【特点和优势】 | LightOx14 is a synthetic analogue of all-trans-retinoic acid (ATRA) that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx14 can be utilized to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy. |
Other Notes【其他说明】 | Chemical Equivalency 1ea=1mg |
Legal Information【法律信息】 | LightOx is a trademark of LightOx Ltd. |
产品性质
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
storage temp.【储存温度】 | 2-8℃ |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |