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Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit

产品编号:4072871
规格:for detection of phospho-stat3 (pTyr705) and pan-stat3 in human, mouse or rat cell and tissue lysates
包装规格:1 KIT
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
40728711 KIT8070
基本信息
NACRES
NA.32
General description【一般描述】
The Phospho-Stat3 (pTyr705) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.
Signal transducers and activators of transcription 3 (STAT3) is a transcription factor that belongs to the family of STAT proteins. The protein contains an Src homology 2 (SH2) domain for protein-protein interactions. STAT3 is activated by phosphorylation on tyrosine 705 by c-Jun N-terminal kinases (JNKs), cytokine receptor-associated kinases, nonreceptor tyrosine kinases, and growth factor receptor tyrosine kinases, in response to growth factors and cytokines. Phosphorylation of STAT3 is important for dimer formation and gene expression. STAT3 mediates the expression of a variety of genes that are involved in cell proliferation and differentiation. It also aids in pro-cancer immunity. The Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA (enzyme-linked immunosorbent assay) is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.
Immunogen【免疫原】
Stat3 (pTyr705) synthetic phosphopeptide, Recombinant Human Stat3
Application【应用】
Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) for quantitative measurement of phosphorylated signal transducer and activator of transcription3 (p-STAT3) in liver tissues.
产品性质
species reactivity
human, rat, mouse
technique(s)
ELISA: suitable
capture ELISA: suitable
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... STAT3(6774)
mouse ... STAT3(20848)
rat ... STAT3(25125)
安全信息
Pictograms【象形图】
GHS05,GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H290 - H335
Hazard Classifications【危险分类】
Met. Corr. 1 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
8B - Non-combustible, corrosive hazardous materials
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