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POVPC

产品编号:4072934
规格:1-palmitoyl-2-(5′-oxo-valeroyl)-sn-glycero-3-phosphocholine, powder
CAS NO:121324-31-0
包装规格:1 MG
产品类别:进口试剂
品牌:Avanti
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
40729341 MG1740
产品别名

121324-31-0

POVPC

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C29H56NO9P
Molecular weight
593.73
NACRES
NA.25
General description【一般描述】
1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) is a derivative of oxidized Low density lipoprotein (oxLDL), a proinflammatory lipid present in atherosclerotic lesions.
Application【应用】
1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) has been used:
  • to study its effects on endothelial function and vasodilation
  • as a ligand for LRP6 in bone marrow mesenchymal stromal cells (MSCs)
  • as a oxidized lipid to study if membrane status at different degrees of lipid peroxidation is involved in oxidative stress tolerance

Biochem/physiol Actions【生化/生理作用】
1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) affects endothelial function by hindering activity of endothelial nitric oxide synthase and stimulating endothelial cell apoptosis. It is implicated in the development of atherosclerosis and it may be used as a potent therapeutic for atherosclerosis.
产品性质
form【形式】
powder
manufacturer/tradename
Avanti Polar Lipids 870606P
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCC([H])=O)=O)COC(CCCCCCCCCCCCCCC)=O)=O
packaging【包装】
5 mL Clear Glass Sealed Ampule (870606P-1mg)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
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