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trihydroxycholestanoic acid
产品别名
547-98-8
trihydroxycholestanoic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H46O5 |
| Molecular weight | 450.65 |
| NACRES | NA.25 |
| General description【一般描述】 | Trihydroxycholestanoic acid (THCA) is an oxidative metabolite of cholesterol and a precursor to bile acids. Very long-chain acyl-CoA synthetase (VLCS) associated with endoplasmic reticulum and peroxisomes activates THCA, the C27 bile acid intermediate. |
| Application【应用】 | Trihydroxycholestanoic acid has been used as a sterol to test its reactivity with human mincle protein. |
| Biochem/physiol Actions【生化/生理作用】 | Trihydroxycholestanoic acid (THCA) and dihydroxycholestanoic (DHCA) accumulation is observed in Zellweger syndrome and cholestatic liver disease. The synthesis of (25R)-isomer of DHCA and THCA is favored by mitochondrial 27-hydroxylase. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 700070P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C27H46O5/c1-15(6-5-7-16(2)25(31)32)19-8-9-20-24-21(14-23(30)27(19,20)4)26(3)11-10-18(28)12-17(26)13-22(24)29/h15-24,28-30H,5-14H2,1-4H3,(H,31,32)/t15-,16?,17+,18-,19-,20+,21+,22-,23+,24+,26+,27-/m1/s1 |
| InChI key | CNWPIIOQKZNXBB-VCVMUKOKSA-N |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (700070P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
