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Amino-PEG6-t-Butyl Ester

产品编号:4074658
CAS NO:1286281-32-0
包装规格:250 MG,1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
4074658250 MG1540
40746581 G5340
产品别名

1286281-32-0

Amino-PEG6-t-Butyl Ester

H2N-PEG6-CH2CH2COOtBu

tert-Butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C19H39NO8
Molecular weight
409.51
MDL number
MFCD13184944
Application【应用】
This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
Legal Information【法律信息】
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
产品性质
form【形式】
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index【折射率】
n/D 1.4562
density
1.06581 g/mL
storage temp.【储存温度】
−20℃
SMILES string
NCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O
NCCOCCOCCOCCOCCOCCOCCC(OC(C)(C)C)=O
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
WGK 3
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