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BocNH-PEG5-acid
产品别名
890152-41-7
BocNH-PEG5-acid
2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azadocosan-22-oic acid
Boc-NH-PEG5-CH2COOH
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H33NO9 |
| Molecular weight | 395.45 |
| Application【应用】 | This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG5-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation. |
| Legal Information【法律信息】 | PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license |
产品性质
| form【形式】 | liquid |
| reaction suitability | reaction type: Pegylations reagent type: cross-linking reagent |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OC(COCCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O OC(COCCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
