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SB 203580, Hydrochloride-CAS 869185-85-3-Calbiochem
产品编号: | 4075249 |
规格: | SB 203580, Hydrochloride, CAS 869185-85-3, is a water-soluble form of SB 203580. A highly potent, selective, ATP-competitive inhibitor of p38 MAP Kinase (IC50 = 34 nM in vitro, 600 nM in cells). |
CAS NO: | 869185-85-3 |
包装规格: | 1 MG,10 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4075249 | 1 MG | 2380 | |||
4075249 | 10 MG | 4730 |
产品别名
869185-85-3
SB 203580, Hydrochloride-CAS 869185-85-3-Calbiochem
4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, HCl, p38 MAP Kinase Inhibitor XVI, Hydrochloride
基本信息
Empirical Formula【经验(实验)分子式】 | C21H16FN3OS · xHCl |
Molecular weight | 377.43 (free base basis) |
General description【一般描述】 | A water-soluble form of the potent MAP kinase inhibitor SB 203580 (Cat. No. 559389). A water-soluble form of the potent MAP kinase inhibitor SB 203580 (Cat. No. 559389). |
Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Product does not compete with ATP. Reversible: no Primary Target p38 MAP kinase Target IC50: 34 nM against p38 MAP kinase in vitro, 600 nM in cells; 50-100 nM against IL-1 and TNF-a production from LPS-stimulated human monocytes and the human monocyte cell line THP-1; 0.2-1.0 µM against platelet aggregation caused by collagen |
Warning【警告】 | Toxicity: Standard Handling (A) |
Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥95% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
color【颜色】 | bright yellow |
solubility【溶解性】 | water: 10 mg/mL DMSO: soluble |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 1, 10 mg in Plastic ampoule |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |