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Rp-8-Br-cGMPS sodium salt
产品别名
208445-06-1
Rp-8-Br-cGMPS sodium salt
Rp-8-Bromo-cGMPS sodium salt
Rp-8-Bromoguanosine- 3′, 5′- cyclic monophosphorothioate sodium salt
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H10BrN5O6PS · Na |
| Molecular weight | 462.15 |
| MDL number | MFCD04037242 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825500 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Rp-8-bromo-cGMPS is a cell permeable cGMP analog that blocks cGMP-dependent protein kinase (cGK, G-kinase, Protein Kinase G, PKG). Rp-8-bromo-cGMPS is resistant to hydrolysis by phosphodiesterases and binds cGK without activating it, resulting in competitive inhibition. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | lyophilized solid |
| color【颜色】 | white to beige |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C1C2=C(N([C@@H]3O[C@H](CO[P@@](O4)([O-])=S)[C@@H]4[C@H]3O)C(Br)=N2)N=C(N)N1.[Na+] |
| InChI | 1S/C10H11BrN5O6PS.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(21-8)1-20-23(19,24)22-5;/h2,4-5,8,17H,1H2,(H,19,24)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-,23-;/m1./s1 |
| InChI key | CHTSSROWUAICIL-GMKUFTCMSA-M |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
