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Anti-Calcium Channel (α1B Subunit) (N-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit
| 产品编号： | 4077022 |
| 规格： | affinity isolated antibody, lyophilized powder |
| 包装规格： | 25 G，1 MG，0.1 MG，100 G，50 μG，0.2 ML，1 KG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4077022 | 25 G | 1340 | |||
| 4077022 | 1 MG | 3210 | |||
| 4077022 | 0.1 MG | 3660 | |||
| 4077022 | 100 G | 4400 | |||
| 4077022 | 50 μG | 5270 | |||
| 4077022 | 0.2 ML | 9960 | |||
| 4077022 | 1 KG | 31340 |
基本信息
| MDL number | MFCD02095951 |
| NACRES | NA.41 |
| General description【一般描述】 | The calcium channel, voltage-dependent, N type, α1B subunit (CACNA1B) or Cav2.2 gene consists of 47 exons and 46 introns, spanning 244kb. The gene is mapped to human chromosome 9q34. The encoded protein is a member of the voltage-gated calcium channel family. |
| Immunogen【免疫原】 | synthetic peptide corresponding to amino acids 851-867 of the α1B subunit of rat brain voltage-gated calcium channel (VGCC, CNB1), with additional N-terminal lysine and tyrosine, conjugated to KLH.1 |
| Application【应用】 | Anti-Calcium Channel (α1B Subunit) (N-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit has been used in immunofluorescence analysis. Anti-Calcium Channel (α1B Subunit) (N-type of Voltage-gated Ca2+ Channel) antibody produced in rabbit is suitable for the following applications:
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunoprecipitation (1 paper) |
| Biochem/physiol Actions【生化/生理作用】 | Calcium channel, voltage-dependent, N type, α1B subunit (CACNA1B) plays a vital role in regulation of trafficking and biophysical properties of voltage-gated calcium channels. Members of voltage-gated calcium channel family act as key transducers of cell surface membrane potential changes to local intracellular calcium transients that initiate various physiological events. The N-type voltage-gated calcium channels (VGCCs) expressed mainly in the neurons, facilitate neurotransmitter release at the sympathetic nerve terminals. CACNA1B is expressed on presynaptic nerve terminals of nociceptors control neurotransmitter release. |
| Physical form【外形】 | Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| mol wt【分子量】 | antigen 210 kDa (low) antigen 240 kDa (high) |
| species reactivity | rat, mouse |
| technique(s) | immunocytochemistry: suitable using rat brain sections immunoprecipitation (IP): suitable western blot: 1:100-1:200 using rat brain membranes |
| UniProt accession no.【UniProt登记号】 | Q02294 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Cacna1b(12287) rat ... Cacna1b(257648) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
